Cavaliers forward Larry Nance Jr. has been diagnosed with a right knee MCL sprain.
The Cavs say he will probably miss 2-4 weeks.
The injury occurred in the first quarter of Tuesday's game against the Pacers.
The Cavs are 8-34 so far this season, which is the worst record in the NBA. They're currently on an 11-game losing streak. The team's leading scorer, Kevin Love, has played in just four games this season.