Printezis was selected by the San Antonio Spurs in the second round with the 58th selection of the 2007 NBA Draft. The draft rights to Printezis were acquired by the Toronto Raptors for their second round draft pick in the 2008 NBA Draft.
In 2006-07 he played for Olympia Larissas BC in Greece, having his best year so far with 11.5 points and 3.9 rebounds per game. In the Greek All-Star Game he won the slam dunk competition. At the end of the year, he was voted as the best young player of the Greek Championship.