Honestly, as an experiment of effectiveness I'd be interested in seeing how using banned substances would change Kobe.

We can all clearly see he hasn't lost any skills or drive but rather he simply cannot do the same things with his body. His millions of repetition are useless now because everything is off slightly (e.g., power when he bends his legs to go up for a jumper). What is amazing is how he hasn't been able to adapt and understand that. Never seen someone be so stubborn about their limitations that even their shot doesn't adapt.

That said - if Kobe had a secret journal and tomorrow was HGH Day 0 i'd be all for it.